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Image Search Results
Journal: Alzheimer's & Dementia
Article Title: Amyloid beta, tau, synaptic, neurodegeneration, and glial biomarkers in the preclinical stage of the Alzheimer's continuum
doi: 10.1002/alz.12131
Figure Lengend Snippet: Cerebrospinal fluid (CSF) biomarker trajectories. The graphs represent the z‐scores changes of each CSF biomarker using the mean and the standard deviation of that CSF biomarker in the A–T– group as a reference. The resulting z‐scores are shown as a function of CSF Aβ42/40 (A) p‐tau (B) or p‐tau/Aβ42 (C) using a robust local weighted regression method. The solid lines depict the trajectory of each CSF biomarker. The dashed lines depict the cutoff for CSF Aβ42/40, p‐tau, and p‐tau/Aβ42, respectively. The horizontal axis direction of CSF Aβ42/40 (A) was inverted.
Article Snippet: The relationship between each CSF biomarker and the proxies of disease progression (ie, CSF Aβ42/40, p‐tau, and p‐tau/Aβ42) were modelled using a robust
Techniques: Biomarker Discovery, Standard Deviation